The following is a list of some of the clubs in the school.
- Research Club
- Junior Achievement Club
- Tax Club
- Drama Club
- Music Club
- Debate Club
- Journalism Club
- Environment Club
- Students’ Campaign Against Drugs (SCAD) Club
- Scouts
- St John’s Ambulance
- President’s Award Scheme
- Aviation Club
- East Africa Community Club
- Lenana School Orchestra
- Cadet Club
- Wildlife Club
- Innovation and Technology Club
- Amani Club
- RoboCode Club
- Computer Club/ICT Club
- Code Surface Club
- Interact/Rotary Club